# Faculty

**Source**: https://biology.mit.edu/faculty-and-research/faculty/?research-area%5B%5D=cancer-biology
**Parent**: https://biology.mit.edu/faculty-and-research/areas-of-research/cancer-biology/

Research AreasBiochemistry, Biophysics, and Structural BiologyCancer BiologyCell BiologyComputational BiologyGeneticsHuman DiseaseImmunologyMicrobiologyNeurobiologyStem Cell and Developmental BiologyLocationsBroad InstituteBuilding 68 - Koch Biology BuildingKoch Institute for Integrative Cancer ResearchNeuroscience ComplexRagon Institute of MGH, MIT and HarvardWhitehead Institute for Biomedical Research

### [Eliezer Calo](https://biology.mit.edu/profile/eliezer-calo/)

Eliezer Calo studies how cells build ribosomes and how dysfunction in ribosome biogenesis and function leads to tissue-specific developmental disorders and cancer.

### [Lindsay Case](https://biology.mit.edu/profile/lindsay-case/)

Lindsay Case studies how molecules are concentrated and organized at the plasma membrane to regulate transmembrane signaling.

### [Jianzhu Chen](https://biology.mit.edu/profile/jianzhu-chen/)

Jianzhu Chen studies the immune system, harnessing the body’s defense force to explore treatment and prevention for cancer, as well as metabolic and infectious diseases.

### [Michael T. Hemann](https://biology.mit.edu/profile/michael-t-hemann/)

Michael T. Hemann uses mouse models to combat cancers resistant to chemotherapy.

### [Whitney Henry](https://biology.mit.edu/profile/whitney-henry/)

Whitney Henry studies ferroptosis in human health and disease with a focus on cancer.

### [David Housman](https://biology.mit.edu/profile/david-housman/)

David Housman studies the biological underpinnings of diseases like Huntington’s, cancer, and cardiovascular disease.

### [Tyler Jacks](https://biology.mit.edu/profile/tyler-jacks/)

Tyler Jacks is interested in the genetic events contributing to the development of cancer, and his group has created a series of mouse strains engineered to carry mutations in genes known to be involved in human cancers.

### [Matthew G. Jones](https://biology.mit.edu/profile/matthew-jones/)

Matthew Jones integrates computational and technological advances to decode the molecular processes underlying spatiotemporal tumor evolution, with a focus on genomic instability and extrachromosomal DNA.

### [Sally Kornbluth](https://biology.mit.edu/profile/sally-kornbluth/)

President of MIT

Sally Kornbluth is President of MIT.

### [Douglas Lauffenburger](https://biology.mit.edu/profile/douglas-lauffenburger/)

Douglas Lauffenburger fosters the interface of bioengineering, quantitative cell biology, and systems biology to determine fundamental aspects of cell dysregulation — identifying and testing new therapeutic ideas.

### [Jacqueline Lees](https://biology.mit.edu/profile/jacqueline-lees/)

Jacqueline Lees develops mouse and zebrafish models, identifying the molecular pathways leading to tumor formation.

### [Alison E. Ringel](https://biology.mit.edu/profile/alison-e-ringel/)

Alison E. Ringel seeks to understand the molecular adaptations that enable immune cells to function and survive within unfavorable environments.

### [Francisco J. Sánchez-Rivera](https://biology.mit.edu/profile/francisco-j-sanchez-rivera/)

Francisco J. Sánchez-Rivera aims to understand how genetic variation shapes normal physiology and disease, with a focus on cancer.

### [Phillip A. Sharp](https://biology.mit.edu/profile/phillip-a-sharp/)

Professor Emeritus

Before closing his lab, Phillip A. Sharp studied many aspects of gene expression in mammalian cells, including transcription, the roles of non-coding RNAs, and RNA splicing.

### [Yadira Soto-Feliciano](https://biology.mit.edu/profile/yadira-soto-feliciano/)

Yadira Soto-Feliciano studies chromatin and epigenetic regulation in normal development and cancer.

### [Stefani Spranger](https://biology.mit.edu/profile/stefani-spranger/)

Stefani Spranger studies how the body’s immune system interacts with growing tumors to harness the immune response to fight cancer.

### [Matthew Vander Heiden](https://biology.mit.edu/profile/matthew-vander-heiden/)

Matthew Vander Heiden is interested in the role that cell metabolism plays in mammalian physiology, with a focus on cancer.

### [Robert A. Weinberg](https://biology.mit.edu/profile/robert-a-weinberg/)

Robert A. Weinberg studies how cancer spreads, what gives cancer stem-cells their unique qualities, and the molecular players involved in the formation of cancer stem cells and metastases.

### [Michael B. Yaffe](https://biology.mit.edu/profile/michael-b-yaffe/)

Michael B. Yaffe studies the chain of reactions that controls a cell’s response to stress, cell injury, and DNA damage.

### [Omer H. Yilmaz](https://biology.mit.edu/profile/omer-h-yilmaz/)

Omer H. Yilmaz explores the impact of dietary interventions on stem cells, the immune system, and cancer within the intestine.

### [Richard A. Young](https://biology.mit.edu/profile/richard-a-young/)

Richard A. Young explores how and why gene expression differs in healthy versus diseased cells.