# A community-consensus reconstruction of Chinese Hamster metabolism enables structural systems biology analyses to decipher metabolic rewiring in lactate-free CHO cells

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## A community-consensus reconstruction of Chinese Hamster metabolism enables structural systems biology analyses to decipher metabolic rewiring in lactate-free CHO cells

<https://doi.org/10.1101/2025.04.10.647063>

Authors

Pablo Di Giusto
,
Dong-Hyuk Choi
,
Athanasios Antonakoudis
,
Vikash Gokul Duraikannan
,
Pierrick Craveur
,
Nicholas Luke Cowie
,
Tejaswini Ganapathy
,
Kannan Ramesh
,
Santiago Benavidez-López
,
Camila A. Orellana
,
Natalia E. Jiménez
,
Leo Alexander Dworkin
,
James Morrissey
,
Igor Marin de Mas
,
Benjamin Strain
,
Norma A. Valdez-Cruz
,
Mauricio A. Trujillo-Roldán
,
Jannis Marzluf
,
Verónica S. Martínez
,
Leopold Zehetner
,
Claudia Altamirano
,
Ana Maria Vega-Letter
,
Bradley Priem
,
Haoyu Chris Cao
,
Martin Hold
,
Junyu Ma
,
Yi Fan Hong
,
Saratram Gopalakrishnan
,
Blaise Manga Enuh
,
Chaimaa Tarzi
,
Kuin Tian Pang
,
Claudio Angione
,
Jürgen Zanghellini
,
Cleo Kontoravdi
,
Hooman Hefzi
,
Michael J. Betenbaugh
,
Lars K. Nielsen
,
Meiyappan Lakshmanan
,
Dong-Yup Lee
,
Anne Richelle
,
Nathan E. Lewis

Preprint Server

bioRxiv

A community-consensus reconstruction of Chinese Hamster metabolism enables structural systems biology analyses to decipher metabolic rewiring in lactate-free CHO cells Pablo Di Giusto, Dong-Hyuk Choi, Athanasios Antonakoudis, Vikash Gokul Duraikannan, Pierrick Craveur, Nicholas Luke Cowie, Tejaswini Ganapathy, Kannan Ramesh, Santiago Benavidez-López, Camila A. Orellana, Natalia E. Jiménez, Leo AlexanderDworkin, James Morrissey, Igor Marin de Mas, Benjamin Strain, Norma A. Valdez-Cruz, Mauricio A. Trujillo-Roldán, Jannis Marzluf, Verónica S. Martínez, Leopold Zehetner, Claudia Altamirano, Ana Maria Vega-Letter, Bradley Priem, Haoyu Chris Cao, Martin Hold, Junyu Ma, Yi Fan Hong, Saratram Gopalakrishnan, Blaise Manga Enuh, Chaimaa Tarzi, Kuin Tian Pang, Claudio Angione, Jürgen Zanghellini, Cleo Kontoravdi, Hooman Hefzi, Michael J. Betenbaugh, Lars K. Nielsen, Meiyappan Lakshmanan, Dong-Yup Lee, Anne Richelle, Nathan E. LewisbioRxiv 2025.04.10.647063

Preprint link: <https://www.biorxiv.org/content/10.1101/2025.04.10.647063v1.abstract>