Otger Campàs Group
Source: https://physics-of-life.tu-dresden.de/team/pol-groups/campas Parent: https://physics-of-life.tu-dresden.de/contact
Physics of Embryonic Self-Organization and Morphogenesis
Our Research Mission
One of the most remarkable properties of living matter is its ability to self-organize into an impressive variety of forms and build functional structures. From the functional morphologies of tissues and organs to the geometry of cells, genetic information must be translated into the physical world to reproducibly shape biological systems. This process involves key molecular events, but also essential physical mechanisms that spatiotemporally guide the formation of these structures. Understanding such fundamental physical mechanisms, the physical nature of living matter, as well as the interplay between physical, molecular and genetic aspects of embryonic self-organization (i.e., mechanochemical feedbacks) remains a major challenge.
Our group has developed novel techniques to directly quantify the spatiotemporal changes of key physical fields during embryonic development. These tools open new avenues to approach the questions described above, as well as mechanobiology, in an in vivo context. Using these unique techniques, we are studying a variety of systems to better understand the physical nature of multicellular systems, the physical mechanisms of cell and tissue/organ morphogenesis, and the mechanochemical feedbacks controlling tissue homeostasis and growth. In particular, we are studying the role of fluid-to-solid transitions (jamming/glass transitions) in embryonic development, how cells spatiotemporally control tissue fluidization, the interplay between signaling events and the physical state of the tissue, the physics of tumor growth, cell morphogenesis, and more.
We’re hiring!
We have multiple open positions for postdocs, graduate students and techs in our new PoL lab, located at the MPI-CBG. If you are interested in Biological Physics of embryonic development and would like to join us,
- check out Open Positions for current job offers or
- email me!
Research Avenues
- RA1 – Collective Transitions in Multicellular Systems (Primary Affiliation)
- RA3 – Self-Organizing Active Molecular Systems
- RA4 – Energy and Information Flows in Active Matter
- RA5 – Physical Measurements in Intact Living Systems
- RA6 – Engineering Living Matter
- RA7 – Bio-Data Science and Physics-Informed AI
News
- 1 July 2025\ HFSP Postdoctoral Fellowship for Augusto Ortega Granillo (article in PoL news)
- 21 February 2025\ Turning Robotic Ensembles into Smart Materials that Mimic Life (article in PoL news)
- 12 August 2024\ The Hidden Architect: How nuclei organize the eyes and brain (article in PoL news)
- 3 July 2024\ The Sächsische Newspaper Interviews PoL Director Otger Campàs (article in PoL news)
- 3 April 2024\ Pressured to become the organizer (article in PoL news)