Endosmart
Source: https://digitalhealth.tu-dresden.de/projects/next-generation-endoscopy/ Parent: https://digitalhealth.tu-dresden.de/career-education/students/clinicum-digitale/
Shaping the future of endoscopy
Endoscopy has transformed gastrointestinal disease diagnosis and treatment through minimally invasive procedures using flexible endoscopes and endoscopic capsules. Our interdisciplinary team of physicians, engineers, and computer scientists is advancing this field.
Our innovations include radar endoscopy for non-contact tissue visualization, intelligent sedation methods, and advanced AI for improved diagnosis and treatment. Additionally, we focus on teaching with new simulator- and software-based methods.
Our comprehensive approach covers diseases, treatment, endoscopy mechanics, image recognition, signal processing, tissue sampling, training simulators, and new technical procedures.
Funded by
Talk about Endoscopy!
Dr. Franz Brinkmann and Dipl.-Ing. Konrad Henkel explain the differences between current and future technology and the development of their prototype: a laparoscope with a deflectable tip.
Endosmart
Endoscopy has transformed GI diagnostics, but endoscope design has changed little in 40 years. This project develops advanced robotic tools with digital control and improved flexibility, enabling precise dissection and better training via simulators. Partners include University Hospital Dresden, TU Dresden, and industry collaborators, funded by EKFZ, SAB, and Volkswagen Foundation.
enDDo.AI
The enDDo.AI project uses advanced AI technologies, including foundation models, to analyze video data from various endoscopic procedures. It aims to develop tools that reduce physician workload, detect complications early, and improve patient outcomes. Current research focuses on video capsule endoscopy and ERCP to enhance diagnostic accuracy, support decisions, and streamline workflows.
MultiMOD Fibre Endoscopy
As part of the ESF Plus project MultiMOD, researchers from the Department of Gastroenterology at University Hospital Dresden and the Chair of Microsystems at TU Dresden are developing next-generation fiber-optic endoscopes. The focus is on extreme functional integration and miniaturization, combining tactile and kinaesthetic sensors, AI-based tip actuation, autonomous navigation, and chemical sensing for advanced tissue analysis.
Autonomous Endoscopy Training
Endoscopy training is a time-consuming and non-standardized process. Unlike laparoscopic surgery, there are no autonomous training courses available for prospective endoscopists to train independently. Therefore, we aim to develop independent endoscopy training courses with the help of software, allowing for independent practice.
Radar Scope
Navigation challenges in endoscopy can lead to complications. This project explores radar-based imaging as an alternative to optical methods, aiming to improve navigation, reduce injury risk, and enhance outcomes. It is a collaboration between University Hospital Dresden, TU Dresden’s High-Frequency Technology Chair, and Vmed, focused on advancing transmural imaging.
Active Intelligent Capsule Endoscopy
As part of BMFTR Cluster4Future SEMECO, partners are developing an intelligent capsule endoscope with adaptive anchoring, biopsy capabilities, and a broadband chemical sensor for in vivo microbiome mapping, involving University Hospital Dresden, TU Dresden, Renesas Dresden, and Ovesco.
Sedation AI
The aim of SedAi is to use objective vital parameters to enable automated sedation monitoring and reduce complications during endoscopic procedures. Vital signs are recorded throughout. The project involves institutions across Germany, including Dresden, under the leadership of University Hospital Halle, to automate and improve sedation in endoscopy.
Clinical Research
Our research focuses on advanced endoscopic procedures such as ERCP and EUS-guided interventions. We have studied bleeding risks in necrosis drainage using lumen-apposing metal stents, bile duct stent migration, and material factors affecting long-term outcomes. Current projects explore EUS-guided biopsies and PEG techniques.
Publications
2026
Werner, J., Bause, O., Oexle, J., Le Floch, M., Brinkmann, F., Hampe, J., & Bringmann, O. (2026). Seeing More with Less: Video Capsule Endoscopy with Multi-task Learning. In: Wu, S., Shabestari, B., & Xing, L. (Eds.), Applications of Medical Artificial Intelligence (Lecture Notes in Computer Science, vol. 16206), Springer, doi: 10.1007/978-3-032-09569-5_2
Werner, J., Oexle, J., Bause, O., Le Floch, M., Brinkmann, F., Tolle, H., Hampe, J., & Bringmann, O. (2026). Reliable mislabel detection for video capsule endoscopy data. arXiv, doi: 10.48550/arXiv.2602.06938
2025
Le Floch, M., Werner, J., McIntyre, L., Wolf, F., Steinhäuser, J., Hampe, J., Langanke, R., Kirk, S., Stopp, C., Geissler, M. E., Brinkmann, F., & Herzog, N. (2025). Advancing video capsule endoscopy with edge AI: A public multi-center capsule dataset with multi-label annotations. Endoscopy, doi: 10.1055/s-0045-1805505
Werner, J., Gerum, C., Nick, J., Le Floch, M., Brinkmann, F., Hampe, J., & Bringmann, O. (2025). Enhanced anomaly detection for capsule endoscopy using ensemble learning strategies. 47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), doi: 10.1109/EMBC58623.2025.11253055
Le Floch, M., Wolf, F., McIntyre, L., Weinert, C., Palm, A., Volk, K., Herzog, P., Kirk, S. H., Steinhäuser, J. L., Stopp, C., Geissler, M. E., Herzog, M., Sulk, S., Kather, J. N., Meining, A., Hann, A., Palm, S., Hampe, J., Herzog, N., & Brinkmann, F. (2025). Galar – a large multi‑label video capsule endoscopy dataset. Scientific Data, doi: 10.1038/s41597-025-05112-7
Pietsch, M., Henkel, K., Körbitz, R., Hüttner, R., Uhlig, K., Bruk, S., Fischer, M., Hampe, J., Richter, A., & Brinkmann, F. (2025). A deflectable video camera system for laparoscopic surgery based on shape memory alloy actuators. Scientific Reports, doi: 10.1038/s41598-025-95898-8
Steinhäuser, J. L., Berzin, T. M., Geissler, M. E., Weber, C., Herzog, N., Le Floch, M., Brückner, S., Hampe, J., Elamin, S., Troya, J., Hann, A., & Brinkmann, F. (2025). Implementing Endoscopy Video Recording in Routine Clinical Practice: Strategies from Three Tertiary Care Centers. Endoscopy International Open, doi: 10.1055/a-2592-3338
Steinhäuser, J., Rapprich, A., Kolbig, A., Stopp, C., Langanke, R., Kirk, S., Le Floch, M., Brückner, S., Hampe, J., & Brinkmann, F. (2025). The Dresden Endoscopy Dataset for Endoscopic Retrograde Cholangiopancreatography. Endoscopy, doi: 10.1055/s-0045-1805573
Le Floch, M., Werner, J., McIntyre, L., Wolf, F., Steinhäuser, J., Hampe, J., Langanke, R., Kirk, S., Stopp, C., Geissler, M. E., Brinkmann, F., & Herzog, N. (2025). Advancing Video Capsule Endoscopy with Edge AI: A Public Multi-Center Capsule Dataset with Multi-Label Annotations. Endoscopy, doi: 10.1055/s-0045-1805505
Langanke, R., Huettner, R., Richter, A., Kirk, S., Geißler, E., Steinhäuser, J., Le Floch, M., Stopp, C., Brückner, S., Hampe, J., & Brinkmann, F. (2025). LearnEndo: A Simulator for Autonomous Endoscopy Training with Software-Based Supervision and Feedback. Endoscopy, doi: 10.1055/s-0045-1806537
2024
Fischer, M., Santoro, L. A., Bruk, S., Henkel, K., Hüttner, R., Körbitz, R., Brinkmann, F., Spickenheuer, A., Kühnert, I., Hampe, J., & Uhlig, K. (2024). Friction testing of tube-guided electrically heated Nitinol shape-memory alloy wires. Tribology International, doi: 10.1016/j.triboint.2023.109161
Uhlig, K., Bruk, S., Fischer, M., Henkel, K., Brinkmann, F., Körbitz, R., Hüttner, R., Pietsch, M., Hempel, P., Spickenheuer, A., Stommel, M., Richter, A., & Hampe, J. (2024). Design, simulation and experimental analysis of a monolithic bending section for enhanced maneuverability of single use laparoscopic devices. Scientific Reports, doi: 10.1038/s41598-024-53914-3
Brinkmann, F., Uhlig, K., Sambale, A., Stommel, M., Berning, M., Babatz, J., Sulk, S., Krasz, S., Schmelz, R., Brückner, S., Hampe, J., & Zeissig, S. (2024). Anchoring fins of fully covered self-expandable metal stents affect pull-out force and stent migration. Gastrointestinal Endoscopy, doi: 10.1016/j.gie.2023.10.036
Brinkmann, F, Uhlig K, Sambale A, Stommel M, Berning M, Babatz J, Sulk S, Krasz S, Schmelz R, & Brückner S. (2023) Biomechanical Pull-out Force of Fully Covered Self-Expanding Metal Stents Predicts Stent Migration in Distal Biliary Stenoses.Endoscopy, doi: 10.1055/s-0043-1765027
2023
Dorausch, E. M. G., Swist, D., Herzog, M., Statz, C., Kober, J., Kühnöl, C., Trittler, T., Martens, N., Brinkmann, F., Hampe, J., & Fettweis, G. (2023). Adoption and evaluation of a multistatic Fourier-based synthetic aperture radar method for ultrasound imaging. Journal of Medical Imaging, doi: 10.1117/12.2653898
2022
Brinkmann, F., Henkel, K., Körbitz, R., Hüttner, R., Uhlig, K., Fischer, M., Alexander, M. H. D., Bodo, M. S. D., Sebastian, M. H. D., Clemens, M. S. D., Jochen, M. H. D., & Richter, A. (2022). Entwicklung einer universellen Aktorplattform aus Formgedächtnislegierungen für Laparoskopie und Endoskopie. Zeitschrift für Gastroenterologie, doi: 10.1055/s-0042-1755113
Brinkmann, F., Hüttner, R., Mehner, P. J., Henkel, K., Paschew, G., Herzog, M., Martens, N., Richter, A., Hinz, S., Groß, J., Schafmayer, C., Hampe, J., Hendricks, A., & Schwandner, F. (2022). Temperature profile and residual heat of monopolar laparoscopic and endoscopic dissection instruments. Surgical Endoscopy, doi: 10.1007/s00464-021-08804-4
2021
Brinkmann, F., Hampe, J., & Zeissig, S. (2021). Thoracic Pain and Pericardial Effusion in a Patient With Chronic Pancreatitis. Gastroenterology, doi: 10.1053/j.gastro.2020.10.050
Research Team
Group Leader
- Dr. med. Franz Brinkmann | Medical Doctor/Clinician Scientist\ University Hospital Carl Gustav Carus | Medical Department I, Gastroenterology
Coordination
- Catrein Stopp | Project Manager | catrein.stopp@ukdd.de\ University Hospital Carl Gustav Carus | Medical Department I, Gastroenterology
Patronage
- Prof. Dr. med. Jochen Hampe
- Prof. Andreas Richter
Team
- Dr. med. Sophie Kirk | Medical Doctor/Clinician Scientist\ University Hospital Carl Gustav Carus | Medical Department I, Gastroenterology
- Dr. med. Jonas Steinhäuser-Meerz | Medical Doctor/Clinician Scientist\ University Hospital Carl Gustav Carus | Medical Department I, Gastroenterology
- Maxime le Floch | Medical Doctor/Clinician Scientist\ University Hospital Carl Gustav Carus | Medical Department I, Gastroenterology
- Hannah Tolle | Medical Doctor/Clinician Scientist\ University Hospital Carl Gustav Carus | Medical Department I, Gastroenterology
- Katharina Böhnke | Endoscopy Nurse\ University Hospital Carl Gustav Carus | Medical Department I, Gastroenterology
- Alexander Zech | Biomedical Engineer\ University Hospital Carl Gustav Carus | Medical Department I, Gastroenterology
- Konrad Henkel | Engineer\ Professorship of Microsystems Engineering, Gastroenterology
- Ronny Hüttner | Engineer\ Professorship of Microsystems Engineering, Gastroenterology
- Rene Körbitz | Engineer\ Professorship of Microsystems Engineering, Gastroenterology
- Malte Pietsch | Engineer\ Professorship of Microsystems Engineering, Gastroenterology
- Lucas Woodworth | Engineer\ EKFZ
Associated Members
- Kai Uhlig | Leibniz Institute of Polymer Research Dresden
- Sascha Bruk | Leibniz Institute of Polymer Research Dresden
- Yuhao Shi| Leibniz Institute of Polymer Research Dresden
- Maximilian Hermsdorf | Chair of High Frequency Technology
Student Members
- Anni Lawniczak | Medicine
- Alexandra Kolbig | Medicine
- Anton Andre Rapprich | Computer Science
- Felix Wilde | Computer Science
Disclaimer
Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the granting authority nor can the granting authority be held responsible for them.