Physical Measurements in Intact Living Systems
Source: https://physics-of-life.tu-dresden.de/research/vision-research-avenues/ra5-physical-measurements-in-intact-living-systems Parent: https://physics-of-life.tu-dresden.de/
Research Avenue 5
- Research Avenue 1RA1
- Research Avenue 2RA2
- Research Avenue 3RA3
- Research Avenue 4RA4
- Research Avenue 6RA6
- Research Avenue 7RA7
Physical Measurements in Intact Living Systems
Identifying physical principles of spatiotemporal self-organization in living cells and tissues requires quantitative measurements of key physical quantities. Currently, progress is limited by our ability to perform accurate measurements of physical quantities in a controlled and minimally invasive way within living systems. The development of new measurement techniques will bring our understanding of the physical basis of life to a new level.
Our aimis to develop technologies, or extend existing ones, that enable measurements of physical quantities that cannot currently be measured inside intact living systems. This includes electrical fields, material properties, mechanical stresses, osmotic and hydrostatic pressures, and flows of matter and energy. Additionally, we will develop smart robotic microscopy methods and AI-based approaches to perform high-throughput measurements of distributions of fluctuating physical quantities in intact cells, tissues and organisms.
Research Topic 1
Quantifying Rates and Flows in Living Matter
Research Topic 2
Mechanical and Electrical Measurements Across Scales
Research Topic 3
Revealing Energetics in Space and Time
Research Topic 4
A Robotic Lab for Generating Large Datasets
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RA Leading Team
Stephan W. Grill (RA Leader)
MPI-CBG | Director of MPI-CBG, Professor for Physics of Life
Physics of Life
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(RA Leader) in a new tab
© MPI-CBG
Elisabeth Fischer-Friedrich (RA Co-Leader)
Heisenberg Professor for Mechanics of Active Biomaterials
Mechanics of Active Biomaterials
hired by PoL
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(RA Co-Leader)
Elias Barriga
Research Group Leader
Biophysical Mechanisms of Morphogenesis
hired by PoL
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Carsten Werner
IPF | Professor for Biofunctional Polymer Materials
Biofunctional polymer materials
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PoL Groups
Ellen Adams
Research Group Leader
Physical Chemistry of Biomolecular Condensates
hired by PoL
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Elias Barriga
Research Group Leader
Biophysical Mechanisms of Morphogenesis
hired by PoL
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Jan Brugués
Chair of Spatiotemporal Organization of Subcellular Structures
Spatiotemporal Organization of Subcellular Structures
hired by PoL
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Otger Campàs
Chair of Tissue Dynamics
Physics of Embryonic Self-Organization and Morphogenesis
hired by PoL
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Stefan Diez
TUD B CUBE | Professor for BioNano Tools
Molecular transport in cell biology and nanotechnology
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© TUD CMCB, Magdalena Gonciarz
Miki Ebisuya
Humboldt Professor and Chair of Cell and Tissue Control
Cross-Species Comparison and Manipulation of the Organoid Zoo
hired by PoL
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Elisabeth Fischer-Friedrich
Heisenberg Professor for Mechanics of Active Biomaterials
Mechanics of Active Biomaterials
hired by PoL
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Stephan W. Grill
MPI-CBG | Director of MPI-CBG, Professor for Physics of Life
Physics of Life
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© MPI-CBG
Rita Mateus
Research Group Leader
Biophysical Principles of Vertebrate Growth
hired by PoL
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Ivo F. Sbalzarini
TUD, CSBD | Professor for Scientific Computing for Systems Biology
The MOSAIC Group: Scientific Computing for Image-based Systems Biology
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© MPI-CBG
Carsten Werner
IPF | Professor for Biofunctional Polymer Materials
Biofunctional polymer materials
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Xingbo Yang
Research Group Leader
Bioenergetics of Self-Organization
hired by PoL
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PoL Associates
Sebastian Aland
HTWD | Professor for Numerical Analysis
Modeling and Simulation of Biological Interfaces
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Michael Brand
TUD CRTD | Professor for Developmental Genetics
Development and Regeneration of the Vertebrate Brain
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Jürgen Czarske
TUD | Professor for Measurement and Sensor Systems
Biomedical Computational Laser Systems (BIOLAS): Adaptive Smart Microscopy
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© Center BIOLAS, TUD
Christian Dahmann
TUD | Professor for Systems Biology and Genetics
Signals and mechanics in epithelial morphogenesis
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Michael Schlierf
TUD B CUBE | Professor for Molecular Biophysics
Conformational changes in biomolecules and enzymes
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© TUD CMCB, Magdalena Gonciarz
Pavel Tomancak
MPI-CBG | Research Group Leader
Patterns of gene expression in animal development
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© MPI-CBG
Jesse Veenvliet
MPI-CBG | Research Group Leader
Stembryogenesis
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© MPI-CBG
Michael Weber
MPI-CBG | Research Group Leader
Nanoscale Optical Bioimaging
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© MPI-CBG