Mechanisms of Regulation of Cell Division Group (MRCDG)
Source: https://www.brookes.ac.uk/research/units/hls/groups/mechanisms-of-regulation-of-cell-division-group Parent: https://www.brookes.ac.uk/engage-and-innovate/consultancy
Group Leader: Dr Victor Bolanos-Garcia
Contact:
About us
The Mechanisms of Regulation of Cell Division Group (MRCDG) undertakes both basic and applied research in the field of cell division control. We are interested in the study of the underlying molecular mechanisms of higher organisms that ensure the proper segregation of the genetic material upon cell division.
We are equally interested in the identification and validation of novel therapeutic targets to interfere with aberrant cell division in cancer cells.
We integrate structural biology methods, including NMR (nuclear magnetic resonance) spectroscopy and protein X-ray crystallography, to study the protein-protein interactions underpinning cell division regulation.
Part of
Leadership
Dr Victor Bolanos-Garcia
Senior Lecturer in Clinical Biochemistry
View profile for Victor Bolanos-Garcia
News
Invitation to contribute to Frontiers in Physiology
We are open to receive contributions to the Research Topic "E3 Ubiquitin Ligases: From Structure to Physiology to Therapeutics, Volume II", which is part of the E3 Ubiquitin Ligases series.
Ubiquitin ligases refers to a family of proteins that are widely distributed in animals and plants and act as key regulators of cell metabolism and cell signaling. Recent reviews nicely describe our current understanding of the function of specific classes of ubiquitin ligases. However, a more holistic account of ubiquitin ligases in health and disease remain as an important pending assignment in the field.
This Research Topic addresses this gap in knowledge and aims to include contributions from leading scientists with a long-standing interest in ubiquitin ligases, ranging from the:
- study of the function and structure of HECT-type, RNA-binding, SCF, E1, and E3 ubiquitin ligase
- alternative Ubiquitin-modification Pathways
- Cullin-RING ubiquitin ligase complex, to the discovery of inhibitors and activators of RING and U-box type E3 Ligases
- role of ubiquitin ligases in autophagy and of ubiquitin-modifying enzymes in the regulation of the immune response.
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Vacancies
We always welcome expressions of interest to join our group as an undergraduate, summer research project, graduate students, postdoctoral fellow or visiting professor. Please get in touch by email (vbolanos-garcia@brookes.ac.uk).
MPhil and PhD studentships
We welcome PhD applications from candidates interested in developing a career in the biomedical sciences and in our programme of research. We accept students that have secured external funding through competitive funding schemes but also self-funded.
For our MRes (one year research-only degree), self-funding is also acceptable. Bear in mind that on top of registration fees and living costs, up to £5,000 is requested to cover the laboratory expenses of the project.
There are a number of schemes for PhD students to apply to.
- Nigel Groome PhD studentship, Oxford Brookes University. Any arising opportunity to join our group will be advertised in our News section but also more widely through our Faculty and University websites, social media, etc).
- We are partners of the Oxford Interdisciplinary Bioscience Doctoral Training Partnership (DTP) programme, a four-year DPhil/PhD programme supported by the Biotechnology and Biological Sciences Research Council (BBSRC) and led by the University of Oxford. The scheme funded some 20 studentships in the biological sciences in the Oxford area including the Pirbright Institute, the Harwell Campus Oxford (Diamond Light Source, ISIS Neutron and Muon Source, STFC Central Laser Facility and the Research Complex at Harwell).
There might be scholarships available in your home country for PhD studies abroad - do investigate these options.
Postdoctoral fellows
Any funding we have for postdoctoral fellows will be advertised on the Working for Brookes page and social media. There might be scholarships available in your home country for postdoctoral experience overseas so you are encouraged to explore these options. We also support applications to request your own funding.
Visiting professors
We are happy to host visiting professors and to support funding applications for this whenever there is an opportunity to create new synergies between our groups/host institutions.
Summer studentship training
We do host one or two undergraduate students from other universities for vacation research training most years, depending on how much space we have and whether we have someone with time to do training and supervision.