# Dental Biomaterials
**Source**: https://www.sharjah.ac.ae/en/Research/RIMHS/DB
**Parent**: https://www.sharjah.ac.ae/en/Research/RIMHS
- #### Overview
- #### Goals and Objectives
- #### Our Team
- #### Publications
- #### Highlights
- #### Collaborations
- #### Lines of Research
- #### Projects
- #### Awards
Dental Biomaterials and Biomimetics Research Group is a newly established interdisciplinary research group at the University of Sharjah, College of Dental Medicine and Research Institute For Medical and Health Sciences. Our main aim is to develop novel natural or synthetic materials and strategies that drive the tissue repair process. We also aim to understand the interaction of biomaterials with the cellular environment to optimize tissue regeneration. Furthermore, we are using new technologies such as artificial intelligence and 3D printing to address a wide variety of clinical challenges and commercial opportunities.
## Goals and Objectives
1. Developing new technology and biomaterials for drug delivery, tissue engineering and regenerative medicine applications.
2. Understanding the complex biomaterials-celluar interaction and their response to various physical and biochemical environments.
3. Contributing to various social needs related to the field of biomaterials.
4. Establishing collaboration and supply services to third bodies such as dental industry and government.
5. Evaluating the anticipated performance of newly introduced dental materials by using clinical simulation and up-to-date technology.
6. Focusing on green products for sustainable dentistry.
#### Prof. Ensanya Ali Abou Neel
##### Research Group Coordinator
[eabouneel@sharjah.ac.ae](mailto:eabouneel@sharjah.ac.ae)
#### Dr. Nadia Khalifa
##### Research Group Member
[n.khalifa@sharjah.ac.ae](mailto:n.khalifa@sharjah.ac.ae)
#### Dr. Betul Rahman
##### Research Group Member
[brahman@sharjah.ac.ae](mailto:brahman@sharjah.ac.ae)
#### Gopinath Vellore Kannan
##### Research Group Memebr
[vgopinath@sharjah.ac.ae](mailto:vgopinath@sharjah.ac.ae)
#### Hatem Mostafa Ibrahim EL Damanhoury
##### Research Group Member
[hdamanhoury@sharjah.ac.ae](mailto:hdamanhoury@sharjah.ac.ae)
#### Dr.Saaid AL Shahedat
##### Research Group Memebr
[salshehadat@sharjah.ac.ae](mailto:salshehadat@sharjah.ac.ae)
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## Research Publications
### No Record Found
Alper Akçay, Melahat Gorduysus, Berdan Aydin, Mehmet Omer Gorduysus. Evaluation of different irrigation techniques on dentin erosion and smear layer removal: A scanning electron microscopy study. Journal of Conservative Dentistry 2022 (In collaboration with Hacettepe University, Ankara, Turkey)
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Ensanya A. Abou Neel, Nadia Khalifa, Manal Awad, S. Soumya, Hussain Alawadhi. Remineralization potential and biocompatibility of titanium dioxide-doped phosphate glasses. Materials Letters 2022, 309 , 131456. This project is funded by the College of Graduate studies & Research/Seed Grant, University of Sharjah, UAE
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Moufti M. A. Nuha Trabulsi, Fattal T., Ghousheh M., Ashira A., Danishvar, S. Developing an Artificial Intelligence Solution to Automate Segmentation of Edentulous Jawbones and Implant Planning. (In collaboration with Brunel University, UK)
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Betul Rahman, Hatem M El-Damanhoury, Soumya Sheela, Hien C Ngo. Effect Of Calcium Silicate, Sodium Phosphate, and Fluoride on Dentinal Tubule Occlusion and Permeability in Comparison to Desensitizing Toothpaste: An In Vitro Study Operative Dent. 2021;46(6):641-649. This project is funded by University of Sharjah/competitive grant.
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Vellore Kannan Gopinath, Soumya Sheela Aravind, Fatma Mousa AlGhalban, Khalil Abdelrazek Khalil Abdelmawgoud and Tahar Laoui. Calcium embedded electrospinning microfibers and bone/dental pulp dentin regeneration for future application in periodontal and oral surgical procedures. This project is funded by University of Sharjah/competitive grant.
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Dr. Mohannad Nassar and his group investigating IP6's role in improving the characteristics of dental materials and its potential utilization in orthodontics, implant and pediatric dentistry and its use as an alternative to phosphoric acid (etchant) and EDTA (chelating agent) in adhesive dentistry and Endodontics.
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Prof. Rani Samsudin and his group investigating the bone regenerative potential of in-house prepared 3-D decellularized and demineralized bone scaffolds as alternative to autografts.
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Richtext Component
1. Biomimetic Materials for Soft and Hard Tissue Regeneration
2. Digital Dentistry
3. Laser and Artificial Intelligence in Dentistry
4. Salivary Biomarkers
## Projects
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| **Active Internal Grant** | | | | | |
| **#** | **Title** | **PI** | **Co-PIs** | **Amount** | **Dates** |
| | **Targeted Grant**, Development of porous calcium polyphosphate ‘rings’ for bone augmentation around endosseous dental implants – 200,000 AED. | Prof. Rani | Prof. Ensanya Abou Neel Prof. Sausan Alkawas Dr. Hani Salama | 200,000 AED | 2023 |
| | **Competitive Grant** Fabrication and characterization of anti-inflammatory 3-D Porous Electrospun Nanofibrous Polycaprolactone/Chitosan Membrane loaded with BMP-2 and/or Vitamin D for Periodontal Regeneration. | Prof. Ensanya Abou Neel | Prof. Susan Alkawas Prof. Khalil Abdelrazek Dr Soumya | 120,000 AED | 2023 |
| | **Targeted Grant-** Injectable Porous Calcium Phosphate Glass Microspheres As OrthoBiologics’ Carrier for Extracellular Vesicles for Pulp Regeneration. | Prof. Ensanya Abou Neel | Prof. Rani Dr Kamis Dr Aghila | 200,000 AED | 2023 |
| | Development, characterization and biological evaluation of a novel graphene deposition technique for optimising the osteogenic and antimicrobial properties of dental implants and prosthesesscaffold loaded with basic fibroblast growth factor for dental pulp tissue regeneration. Grant No. (V.C.R.G. / R. 447/2022), 120,000 AED for 36 months, University of Sharjah, Sharjah, United Arab Emirates. | Dr. Mohammad-Adel Moufti | Prof. Rani Samsudin Prof. Abdul Hai Alami Prof. Ensanya Abou Neel Prof. Mohamad Hamad Prof. Zahi Badran Dr. Soumya Aravind | 120,000 AED | 2022-till now |
| | Antimicrobial efficacy and biocompatibility of green synthesized silver and copper oxide nanoparticles capped with Barleria prionitis on oral pathogens | Dr. Sunaina Shetty | Dr. Venkateshbabu N Prof. Ensanya Abou Neel | 95000 AED | 2022-2024 |
| | Development of a thermo-sensitive nanomaterial hydrogel for regenerative endodontic treatment | Dr. Venkateshbabu N | Dr. Sunaina Shetty Prof. Ensanya Ali Abou Neel | 119500 AED | 2023-2025 |
| | Investigation of PLGA/TCP Scaffold Loaded with Basic Fibroblast Growth Factor for Dental Pulp Tissue Regeneration | Dr. Saaid Al Shehadat | Prof. Ensanya Abu Neel Prof. Khalil Abdelrazek Khalil Abdelmawgoud | 120,000 AED | November 2022 |
| | Effects of Ramadan intermittent fasting on patients with gingivitis and periodontitis: A prospective cohort study using inflammatory, microbiomic, and metabolomics markers | Dr. Saaid Al Shehadat | Dr Moez AlIslam Fares Dr Mohamed Ibrahim Madkour | 120,000 AED | November 2022 |
| | Mechanical Properties of Traverse™ Rotary Glide Path File | Prof. Ahmed Jamleh | | 40,000 AED | March 2024- July 2025 |
| | Phytic Acid: A Green and Sustainable Product in Endodontics | Dr. Mohannad Nassar | | 120,000 | Nov-2022 to Nov-2025 |
| | Non-Protein Thiols: A Potential Adjuvant Therapy to Mitigate Side Effects of Teeth Bleaching | Dr. Mohannad Nassar | Dr. David Williams, Dr. Rania Nassar | 116,000 | Nov-2023 to Nov-2026 |
| | Assessment of Novel Salivary Biomarkers by Using Enzyme-linked Immunosorbent Assay (ELISA) and Surface Enhanced Raman Spectroscopy (SERS) in Periodontitis Patients | Dr. Betul Rahman | Prof. Zahi Badran, Dr. Kais Daoudi , Dr. Soumya Sheela Aravind, Prof. Sausan Al Kawas, Dr. Mounir Kaidi | 120000 AED | 2022-2025 |
| | Investigation of the role of common oral conditions and dental restorations on the salivary candidal load Investigation of the role of common oral conditions and dental restorations on the salivary candidal load Grant No. (no# V. C. R. G./ R. 447/2022, 2201100156), 40k DHs for 24 months, University of Sharjah, Sharjah, United Arab Emirates. | Dr. Kamis Gaballah | Prof. Ensanya Abou Neel | 40,000 AED | 2022-till now |
| | Development of an artificial intelligence object detection solution for automatic real-time visual inspection and charting of dental conditions | Dr. Mohammad-Adel Moufti | Dr. Manar Abu Talib, Dr. Qassim Nasir, UOS College of Computing and Informatics | 120,000 | Dec-2023 to Dec-2025 |
| | A Unified Blockchain-Based Electronic Dental Record (EDR) Ecosystem for Secure Data Exchange | Dr. Sohail Abbas, UOS College of Computing and Informatics | Dr. Mohammad-Adel Moufti, CDM Dr. Manar Abu Talib, Dr. Qassim Nasir, Ahmed Bouridane UOS College of Computing and Informatics | 118,000 | Dec 2023- Dec 2025 |
| | Periodontal Health, General and Oral Health Related Quality of Life in Breast Cancer Patients on Aromatase Inhibitors: A Case-Control Study. | Prof. Manal | Dr. Nadia Khalifa Prof. Zahi Badran Prof. Basema Saddek Prof. Wegdan Bani Issa | 174,000 | November 2024-2026 |
| **17** | An evaluation of serum and salivary microRNAs associated with type 2 diabetes and periodontitis” | Dr. Anirudh Acharya | Dr. Jalal Taneera, Prof. Zahi Badran, Dr. Betul Rahman, Dr. Anila Abid | AED 120,000 | 2023-26 |
| **18** | Serum and salivary biomarkers in type 2 diabetes and periodontitis | Dr. Anirudh Acharya | Dr. Jalal Taneera, Prof. Zahi Badran, Dr. Aala Mansour, Dr. Anila Abid | AED 119,500 | 2023-25 |
| **19** | Hybrid layer and micro-tensile bond strength of titanium dioxide-doped phosphate glass microspheres filled universal dental adhesive | Prof Adam | Prof Ensanya, Dr Hatem | AED 34,000.00 | 2022-2025 |
| **20** | Clinical performance of conventional, 3D printed and milled implant-retained mandibular overdentures: a randomized clinical trial | Prof Adam | Dr Ahmed Aziz, Dr Zaid Hamdoon | AED 119,000.00 | 2023-2026 |
| **21** | Clinical performance of conventional, 3D printed and milled single implant-retained mandibular overdentures: a randomized clinical trial | Prof Adam | Dr. Nadia, Prof Zahi, Dr Ibrahim | AED 120,000.00 | 2024-2027 |
| **22** | Clinical performance of mandibular all-on-4 modified polyetheretherketone treatment approach versus conventional metal framework and hybrid prostheses: a randomized clinical trial | Dr Ahmed Aziz | Prof Adam, Dr Zaid Hamdoon, Prof Rani Samsudin | AED 119,000.00 | 2023-2026 |
| **23** | Accuracy evaluation of three intraoral scanners and stereophotogrammetry compared to laboratory scanner for complete-arch implant-supported prosthesis: A prospective study (Co Investigator), AED 120,000.00, University of Sharjah, 2024-2026 | Dr Ahmed Aziz | Prof Adam, Dr Zaid Hamdoon | AED 120,000.00 | 2024-2026 |
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| **Active External Grant** | | | | | | |
| **#** | **Title** | **PI & Co-PIs** | **Cash Amount Transferred to UoS** | **Total Funding (Cash & In-Kind)** | **Dates** | **Funding Organization** |
| - **1** | Impact of Cooling on Shaping Ability of Thermally Treated Files in Canal Models with Double Curvature | Hajar Albanyan, Ahmed Jamleh, Abdulmohsen Alfadley, Khalid Alfouzan | | 85000 | 2022 | King Abdullah International Medical Research Center |
| - **2** | Investigating Novel Strategies for Preventing and Treating Microbial Biofilms Aimed at Combating Oral Infections | Dr. Rania Nassar, Dr. Mohannad Nassar, Dr. David Williams, Dr. Abiola Senok | - | 200,000 | 2024-2026 | MBRU |
| | Unlocking the Potential of IP6: Translating Dental Research into Over-the- Counter Products and Advanced Material Coatings | Dr. Rania Nassar, Dr. Mohannad Nassar, Dr. David Williams, Dr. Abiola Senok | - | 50,000 USD (180,000 AED) | 2024-2026 | IADR |
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| | **| | | | | | --- | --- | --- | --- | | **Recognition of Members -** Research Awards Received by Members/Assistants, Membership of Emirates/National Committees, ..etc. | | | | | **#** | **Member Name** | **Recognition Details & Awarding Organization** | **Dates** | | - **1** | Saaid Al Shehadat | Recognition Award Plaque for patent registration in the USA, at GITEX Global 2024 in Dubai/ Government of Sharjah | October 2024 | | - **2** | Saaid Al Shehadat/Ensanya Abou Neel (MDS student Lubna Albayyari) | The 1st place at the CAD/CAM Digital & Oral Facial Aesthetics 37th International Dental ConfEx - CAPP 2024 in Dubai/ CAPP | November 2024 | | - **3** | Saaid Al Shehadat (Undergraduate student Youmna Ahmad) | The 2nd place at the CAD/CAM Digital & Oral Facial Aesthetics 37th International Dental ConfEx - CAPP 2024 in Dubai/ CAPP | November 2024 | | - **4** | Saaid Al Shehadat (Undergraduate student Shamma) | The 1st place Best Undergraduate research Award in: “Dental Second Appolonia Students’ Symposium” in collaboration with IADR. | April **2025** | | - **5** | Saaid Al Shehadat (Undergraduate student Amal Alsusi) | The 2nd place Best Poster Presentation Award in: “Dental Second s’ Appolonia Symposium Students” in collaboration with IADR. | April 2025 | | - **6** | Mohannad Nassar | Joseph Lister Award Candidate/ IADR | March 2024 | | - **7** | Mohannad Nassar Ahmed Jamleh (Student Mai Samara) | Local Hatton Award Winner and Competitor for the International Hatton Award in USA. | March 2024 | | - **8** | Mohannad Nassar Ahmed Jamleh (student Mai Samara) | The 1st place Best Postgraduate research Award in: “Dental First Appolonia Symposium Students” | April 2024 | | **9** | Mohannad Nassar (Co-investigator) | IADR Innovation in Oral Care Award with the IADR-USA. | June 2024 | | **10** | Hatem Eldamanhoury/Ensanya Abou Neel (Student Mohamed Jarbou) | The 1st place Best Postgraduate research Award in: “Dental Second s’ Appolonia Symposium Students” in collaboration with IADR. | April **2025** | | **11** | Adam bin Husein/Hatem Eldamanhoury/Ibrahim Mahmoud Aziz Aziz (Student Saifeldeen Mamoun Saber) | 2nd place poster presentation winner at the 13th USDSA conference | February 2025 | | **12** | Ahmed Aziz (recipient)/Adam bin Husein (mentor) | The Ivoclar/International College of Prosthodontics Research Fellow in Dental Restorative Materials | 2024/2025 | | **13** | MHD Adel Moufti (Student: Noor Almahmeed) | 3rd place, students’ presentation winner at the AEEDC conference, Dubai | February 2024 | | **14** | MHD Adel Moufti (Student: Zainab Hawlaji) | 2nd place poster presentation winner at the AEEDC conference, Dubai | February 2025 | | **15** | Ensanya Abou Neel | Top 2% Scientists - August 2025 data-update for "Updated science-wide author databases of standardized citation indicators". | 2025 | | | Co-author on: First position, Student poster Competition. Abdulhameed E. A., Aghila Rani K. G., AlGhalban F. M., Abou Neel E. A., Khalifa N., Omar M., Samsudin A.R. Effect of Vitamin C-Incorporated Polycaprolactone Membranes on Oxidative Stress Responses in Bone Regeneration In-Vitro. Exploring Frontiers of Research and Innovation in Dentistry” CUA First International Dental Conference | 25th April 2024, City University Ajman, Ajman, UAE. | | | Co-author on work awarded First Position, Student Poster Competition. Abdulhameed E. A., Aghila Rani K. G., AlGhalban F. M., Abou Neel E. A., Khalifa N., Omar M., Samsudin A.R. The Efficacy of Vitamin C in Antioxidant-designed Biomaterial for Bone Regeneration. 3rd UAE Anatomy & Cellular Biology Conference 24-05-2024 in Khalifa University, Abu Dhabi. | 24-05-2024 in Khalifa University, Abu Dhabi. | | | Ensanya Abou Neel | Supervisor of work awarded First Position – Student Poster Participation in 12th International Students’ Dental Conference-2024 held from 22-23 February 2024 at the University of Sharjah, Sharjah, UAE. bin Youkha S, Ismail A., Khalifa N., Abou Neel E. A. Biocompatibility and Enamel Remineralization Potential of Titanium-Doped Phosphate Glasses With/Without Diode Laser Application. 12 International Students’ Dental Conference-2024 held from 22-23 February 2024 at the University of Sharjah. | 12th International Students’ Dental Conference 2024 held from 22-23 February 2024 at the University of Sharjah. | | | | | |** | | |
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