謝達斌 副校長-國立陽明交通大學
Source: https://www.nycu.edu.tw/nycu/ch/app/artwebsite/view?module=artwebsite&id=426&serno=9d762da8-01ea-4e95-b4f9-7f44e6334866 Parent: https://www.nycu.edu.tw/nycu/ch/app/folder/407
副校長
- 謝達斌 副校長
- 現職
- 國立陽明交通大學副校長
- 國立陽明交通大學牙醫學系教授
- 臺北榮民總醫院醫學研究部牙醫師
- 聯絡資訊
- 電話：(02)2826-7201
- Email：dbshieh@nycu.edu.tw
- 通訊處：11221 臺北市北投區立農街二段155號 副校長室
- 秘書
- 陳姵璇 副管理師
- 電話： 02-28267000 ext. 62248
- Email：phchen2@nycu.edu.tw
【學歷】
- 美國哈佛大學牙醫學院分子生物學醫學科學博士(1991-1997)
- 陽明大學牙醫學系學士(1982-1988)
【經歷】
- 成功大學牙醫學系暨口腔醫學研究所講座教授(2021.01-迄今)
- 成功大學國際巨分子與奈米醫學創新研發中心主任(2013.04-2026.01)
- 成功大學國際奈米醫學中心主任(2018-2026.01)
- 成功大學微奈米科技研究中心特聘研究員(2010.08-迄今)
- 科技部政務次長(2018.09-2020.12)
- 成功大學牙科學科暨口腔醫學研究所特聘教授(2011.08-2020.07)
- 成功大學牙科學科暨口腔醫學研究所科主任兼所長(2009.08-2014.01)
- 成功大學牙科學科暨口腔醫學研究所科教授(2008.0-2011.07)
- 成功大學研究發展處企劃組組長(2007.02-2009.08)\
【榮譽】
- 2024 2024 莫德納台灣mRNA前瞻新創獎
- 2023 2023 未來科技獎
- 2023 國科會特約研究員
- 2021 2021 未來科技獎
- 2020 第十七屆國家新創獎-新創精進獎
- 2020 第十七屆2020 臺北生技獎
- 2020 斐陶斐榮譽學會傑出成就獎
- 2020 中華民國牙醫師公會全國聯合會特殊貢獻銀質獎
- 2019 第十六屆國家新創獎-新創精進獎
- 2018 第十六屆有庠科技獎座(奈米科技領域)
- 2014 2014 IEEE Tainan Section Outstanding Technical Achievement Award\
【研究專長】
- 口腔病理、分子與細胞生物學、結構生物學、腫瘤學、牙科學、奈米生物醫學、生醫光電、粒線體醫學
【代表著作】
- Ngamkham J, Chiangjong W, Wang PW, Shieh DB, Phansri T, Sritanaudomchai H. Synergistic enhancement of anticancer effects by periodontal ligament stem cell exosomes and oxaliplatin via apoptosis induction and protein modulation. Biomed Pharmacother. Published online August 19, 2025. doi:10.1016/j.biopha.2025.118481
- Wei TY, Wu CC, Hsu YT, Lin WH, Tsai LC, Shieh DB, Chang CL. An exploratory analysis of driver gene alterations and their potential prognostic relevance in endometrial cancer with POLE exonuclease domain mutations. Gynecol Oncol. 2025 Aug;199:17-26. doi: 10.1016/j.ygyno.2025.06.006.
- Hwu JR, Panja A, Tsay SC, Huang WC, Lin SY, Yeh CS, Su WC, Yang LX, Shieh DB. β-d-Ribofuranose as a Core with a Phosphodiester Moiety as the Enzyme Recognition Site for Codrug Development. Org Lett. 2024 Nov 22;26(46):9865-9870. doi: 10.1021/acs.orglett.4c03662. Epub 2024 Nov 14.
- Tseng PC, Shieh DB, Kessler A, Kaisarly D, Rösch P, Kunzelmann KH. Direct ink writing with dental composites: A paradigm shift toward sustainable chair-side production. Dent Mater. Published online August 6, 2024. doi:10.1016/j.dental.2024.08.002
- Hsieh CH, Ho PS, Wang WL, Shih FH, Hong CT, Wang PW, Shieh DB, Chang WL, Wang YC. Decreased plasma gelsolin fosters a fibrotic tumor micro-environment and promotes chemoradiotherapy resistance in esophageal squamous cell carcinoma. J Biomed Sci. 31(1):90, Sep.2024
- Yang LX, Lai YH, Cheung CI, Ye Z, Huang TC, Wang YC, Chin YC, Chia ZC, Chen YJ, Li MJ, Tseng HY, Tsai YT, Zhang ZB, Chen KH, Tsai BY, Shieh DB, Lee NY, Tsai PJ, Huang CC. Novel metal peroxide nanoboxes restrain Clostridioides difficile infection beyond the bactericidal and sporicidal activity. Bioeng Transl Med. 2023 Sep 5;8(6):e10593. doi: 10.1002/btm2.10593.
- Loke YL, Beishenaliev A, Wang PW, Lin CY, Chang CY, Foo YY, Faruqu FN, Leo BF, Misran M, Chung LY, Shieh DB, Kiew LV, Chang CC, Teo YY. ROS-generating alginate-coated gold nanorods as biocompatible nanosonosensitisers for effective sonodynamic therapy of cancer. Ultrason Sonochem. 2023 Jun;96:106437. doi: 10.1016/j.ultsonch.2023.106437.
- Asare-Werehene M, Hunter RA, Gerber E, Reunov A, Brine I, Chang CY, Chang CC, Shieh DB, Burger D, Anis H, Tsang BK. The Application of an Extracellular Vesicle-Based Biosensor in Early Diagnosis and Prediction of Chemoresponsiveness in Ovarian Cancer. Cancers (Basel). 2023 Apr 30;15(9):2566. doi: 10.3390/cancers15092566.
- Chiu CT, Cao JK, Wang PW, Wu YN, Lee YC, Jeng YR, Shieh DB, Reisz RR. Mammalian tooth enamel functional sophistication demonstrated by combined nanotribology and synchrotron radiation FTIR analyses. iScience. 2022 Dec 27;26(1):105679. doi: 10.1016/j.isci.2022.105679.
- Shih TM, Hsiao JF, Shieh DB, Tsai GE. Acidic Microenvironment-Sensitive Core-Shell Microcubes: The Self-assembled and the Therapeutic Effects for Caries Prevention. Eur J Dent. 2022 Dec 19. doi: 10.1055/s-0042-1757464.
- Hsieh CH, Kuan WH, Chang WL, Kuo IY, Liu H, Shieh DB, Liu H, Tan B, Wang YC. Dysregulation of SOX17/NRF2 axis confers chemoradiotherapy resistance and emerges as a novel therapeutic target in esophageal squamous cell carcinoma. J Biomed Sci. 2022 Oct 30;29(1):90. doi: 10.1186/s12929-022-00873-4.
- Kong B, Han CY, Kim SI, Patten DA, Han Y, Carmona E, Shieh DB, Cheung AC, Mes-Masson AM, Harper ME, Song YS, Tsang BK. Prohibitin 1 interacts with p53 in the regulation of mitochondrial dynamics and chemoresistance in gynecologic cancers. J Ovarian Res. 2022 Jun 7;15(1):70. doi: 10.1186/s13048-022-00999-x.
- Wu YN, Yang LX, Wang PW, Braet F, Shieh DB. From Microenvironment Remediation to Novel Anti-Cancer Strategy: The Emergence of Zero Valent Iron Nanoparticles. Pharmaceutics. 2022 Jan 2;14(1):99. doi: 10.3390/pharmaceutics14010099. (SCIE)
- Yu CJ, Damaiyanti DW, Yan SJ, Wu CH, Tang MJ, Shieh DB, Liu PP, Liu PY. The Pathophysiologic Role of Gelsolin in Chronic Kidney Disease: Focus on Podocytes. Int J Mol Sci. 2021 Dec 10;22(24):13281. doi: 10.3390/ijms222413281.
- Tsai HY, Chao LC, Chou CH, Lin YH, Huang KC, Hsieh MC, Liao YT, Wang PW, Shieh DB. Enhanced fluorescence signal using stray light shutter in a quantitative PCR chip. Journal of Optics. 2021 Nov. (SCIE)
- Wang PW, Lee WT, Wu YN, Shieh DB. Opportunities for Nanomedicine in Clostridioides difficile Infection. Antibiotics (Basel). 2021 Aug 5;10(8):948. doi: 10.3390/antibiotics10080948. (SCIE)
- Hsieh CH, Hsieh HC, Shih FS, Wang PW, Yang LX, Shieh DB, Wang YC. An innovative NRF2 nano-modulator induces lung cancer ferroptosis and elicits an immunostimulatory tumor microenvironment. Theranostics. 2021 May 13;11(14):7072-7091. doi: 10.7150/thno.57803. (SCIE)
- Kiew LV, Chang CY, Huang SY, Wang PW, Heh CH, Liu CT, Cheng CH, Lu YX, Chen YC, Huang YX, Chang SY, Tsai HY, Kung YA, Huang PN, Hsu MH, Leo BF, Foo YY, Su CH, Hsu KC, Huang PH, Ng CJ, Kamarulzaman A, Yuan CJ, Shieh DB, Shih SR, Chung LY, Chang CC. Development of flexible electrochemical impedance spectroscopy-based biosensing platform for rapid screening of SARS-CoV-2 inhibitors. Biosens Bioelectron. 2021 Jul 1;183:113213. doi: 10.1016/j.bios.2021.113213. Epub 2021 Apr 3. (SCIE)