New Front Cover in ChemSusChem

Source: https://cbr.cs.tum.de/en/news/article/new-front-cover-in-chemsuschem Parent: https://cbr.cs.tum.de/en/news

2025-10-23 CBR

New Front Cover in ChemSusChem

Successful application of microfluidics to improve an enzyme for sustainable fuel production!

We are pleased to highlight the impressive work of our former PhD student Mariko Teshima, that was selected as the front cover of the recent issued of ChemSusChem!

The Front Cover shows a microfluidic chip that was used in an enzyme engineering approach utilizing microdroplet-based UHTS to optimize an aldehyde dehydrogenase towards higher temperature stability and solvent tolerance. The optimized enzyme was then applied as part of a multi-enzyme cascade.

Our ultimate goal is a continuous process for the conversion of glucose into isobutanol in a two-phase system using these enzymes and based on the formation of an isobutanol phase at sufficiently high concentration and with continuous removal of the organic phase.

Find more information in our research article! (DOI: 10.1002/cssc.202501120).