# Cancer immunology

**Source**: https://sites.manchester.ac.uk/lydia-becker-institute/research/cancer-immunology/
**Parent**: https://sites.manchester.ac.uk/lydia-becker-institute/

[Lydia Becker Institute of Immunology and Inflammation](https://sites.manchester.ac.uk/lydia-becker-institute/) / [Research](https://sites.manchester.ac.uk/lydia-becker-institute/research/) / Cancer immunology

- [The Lydia Becker Institute of Immunology and Inflammation](https://sites.manchester.ac.uk/lydia-becker-institute/)
- [Research](https://sites.manchester.ac.uk/lydia-becker-institute/research/)
  - [Barrier immunology](https://sites.manchester.ac.uk/lydia-becker-institute/research/barrier-immunology/)
  - [Cancer immunology](https://sites.manchester.ac.uk/lydia-becker-institute/research/cancer-immunology/)
  - [Cardiovascular immunology and multi-morbidities](https://sites.manchester.ac.uk/lydia-becker-institute/research/cardiovascular-immunology-and-multi-morbidities/)
  - [Cellular immunology](https://sites.manchester.ac.uk/lydia-becker-institute/research/cellular-immunology/)
  - [Eco-immunology and context-specific immunology](https://sites.manchester.ac.uk/lydia-becker-institute/research/eco-immunology-and-context-specific-immunology/)
  - [Immune tolerance](https://sites.manchester.ac.uk/lydia-becker-institute/research/immune-tolerance/)
  - [Immuno-informatics](https://sites.manchester.ac.uk/lydia-becker-institute/research/immuno-informatics/)
  - [Immuno-matrix](https://sites.manchester.ac.uk/lydia-becker-institute/research/immuno-matrix/)
  - [Life course immunology](https://sites.manchester.ac.uk/lydia-becker-institute/research/life-course-immunology/)
  - [Neuro-immunology](https://sites.manchester.ac.uk/lydia-becker-institute/research/neuro-immunology/)
  - [Pathogens, parasites and commensals](https://sites.manchester.ac.uk/lydia-becker-institute/research/pathogens-parasites-and-commensals/)
  - [COVID-19](https://sites.manchester.ac.uk/lydia-becker-institute/research/covid-19/)
- [Study](https://sites.manchester.ac.uk/lydia-becker-institute/study/)
- [Partnerships with impact](https://sites.manchester.ac.uk/lydia-becker-institute/partnerships-with-impact/)
- [Updates](https://sites.manchester.ac.uk/lydia-becker-institute/blog/)
- [About us](https://sites.manchester.ac.uk/lydia-becker-institute/about-us/)
  - [People](https://sites.manchester.ac.uk/lydia-becker-institute/about-us/people/)
  - [Newsletter](https://sites.manchester.ac.uk/lydia-becker-institute/about-us/newsletter/)

# Cancer immunology

Cancer immunology is revolutionising the treatment of cancer. At The University of Manchester, basic researchers and clinicians work closely together to expand our knowledge of the power of the immune system in fighting disease.

To combat immune recognition and elimination, tumours exhibit a plethora of evasive mechanisms.

However, the extent to which the immune system constitutes a natural barrier to cancer has been a long-lasting subject of debate. In the last few years, this notion has gained undisputable support following the clinical success of therapies aimed at harnessing cells from the immune system and limiting immune evasion by tumour cells. These unprecedented and outstanding outcomes – even in cancer types that were until recently considered as refractory to immune-based therapies – have fully reinvigorated the interest in the cancer immunology field.

But complete and durable responses have only been observed in a minority of patients and in selected cancer types. This highlights the need for basic, translational and clinical research to further uncover the mechanism of action of these treatments, and to identify novel immune pathways to target and increase the efficacy of cancer therapy.

[Cancer immunology case study](https://sites.manchester.ac.uk/lydia-becker-institute/research/cancer-immunology/cancer-immunology-case-study/)

## People

### Leads

[Professor Robert Bristow](https://www.research.manchester.ac.uk/portal/robert.bristow.html)

[Dr Santiago Zelenay](http://www.cruk.manchester.ac.uk/Our-Research/Cancer-Inflammation-and-Immunity)

Dr Anne Armstrong

### Principal investigators

[Professor Fiona Thistlethwaite](https://www.christie.nhs.uk/internal-lists/consultant-list/thistlethwaite-fiona/)

Dr Jorgen Barriuso

Dr Ester Baena

[Dr Brian Bigger](https://www.research.manchester.ac.uk/portal/brian.bigger.html)

Dr Anshuman Chaturvedi

[Dr Phil Crosbie](https://www.research.manchester.ac.uk/portal/en/researchers/philip-crosbie(30be2955-b500-43bd-a424-46dbf45f34cf).html)

[Professor Daniel Davis](https://www.research.manchester.ac.uk/portal/daniel.davis.html)

[Professor Caroline Dive](http://www.cancerresearchuk.org/our-research/researchers/professor-caroline-dive)

[Dr Katie Finegan](https://www.research.manchester.ac.uk/portal/k.g.finegan.html)

Dr Avinash Gupta

[Dr Evangelos Giampazolias](https://www.cruk.manchester.ac.uk/Our-Research/Cancer-Immunosurveillance)

[Dr Jamie Honeychurch](https://www.research.manchester.ac.uk/portal/jamie.honeychurch.html)

[Dr Adam Hurlstone](https://www.research.manchester.ac.uk/portal/adam.hurlstone.html)

[Professor Tim Illidge](https://www.research.manchester.ac.uk/portal/tim.illidge.html)

Dr Claus Jorgensen

[Dr Janine Lamb](https://www.research.manchester.ac.uk/portal/janine.lamb.html)

Dr Rebecca Lee

Dr Colin Lindsay

Dr Robert Metcalf

[Dr Kathleen Nolan](https://www.research.manchester.ac.uk/portal/kathleen.nolan.html)

Dr Manon Pillai

Dr Amaya Viros Usandizaga

Dr Tom Waddell

Dr Mark Williams

#### Contact Us

[+44 (0)161 306 3771](tel:+441613063771)

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