# MECAXON

**Source**: https://jerugroup.eng.ox.ac.uk/software/mecaxon
**Parent**: https://jerugroup.eng.ox.ac.uk/software

# MECAXON

MECAXON simulates the conduction of electro-physiological pulses and mechanical pulses in neuronal axons, as well as the interactions between two pulses.

Main features of the code:

- Solved by finite element method in Matlab
- Capable of modelling the conduction of both electro-physiological and mechanical pulses in the axon
- Capturing the direct and reverse flexoelectric effects that occurs in the neuronal membrane
- Can be potentially used to explain physical phenomena related to the mechano-electrophysiological coupling in neurons, such as membrane deformation during action potential propagation and ultrasound neuromodulation

#### [**Download Link**](https://process.innovation.ox.ac.uk/software/p/15910/mecaxon-academic/1)

#### **Relevant publications**

- H. Chen, D. Garcia-Gonzalez and A. Jérusalem. *Computational model of the mechanoelectrophysiological coupling in axons with application to neuromodulation.* **Physical Review E, 99(032406), 2019.** DOI:10.1103/PhysRevE.99.032406